High-Precision pMHC Binding Analysis with BLI (OCTET)
At Tetramer Store, we provide fast, reliable, and high-sensitivity affinity characterization of TCR-mimetic antibodies binding to peptide-MHC (pMHC) complexes. Using Bio-Layer Interferometry (BLI) on the OCTET platform, we deliver precise kinetic data to support antibody discovery, optimization, and preclinical development.
Our Service Workflow
✅ Antibody Production
- High-quality IgG synthesis
✅ BLI Assay Setup
- IgG immobilization on Protein A biosensors
- Optimized surface loading to ensure consistent binding
✅ Affinity & Kinetics Measurement
- Real-time interaction analysis with pMHC in solution
- Calculation of ka (association rate), kd (dissociation rate), and KD (affinity constant)
- Full kinetic characterization for lead selection
Why Choose Us?
🔬 High Sensitivity – BLI allows label-free detection with precise kinetic measurements.
⏳ Fast Turnaround – From antibody production to affinity determination in weeks.
📊 Comprehensive Data Reporting – Clear, publication-ready kinetic analysis.
🔁 Flexible & Customizable – Tailored protocols for your specific pMHC-antibody interactions.
Get Started Today
Need reliable affinity characterization for your TCR-mimetic antibody? Contact us to discuss your project and receive a custom proposal.
📩 ordering@tetramerstore.com 🌐 www.tetramerstore.com