Empty Loadable Tetramers

More flexible workflow with ELT MHC Tetramers.

Discover the next generation of T cell detection with our Empty Loadable MHC Tetramers. Offering unparalleled flexibility, these tetramers allow you to load your own peptides, achieving faster results with brighter staining at a fraction of the cost. With our product, you can stain antigen-specific T cells in just minutes.

 

Why Choose Our Empty Loadable Tetramers?

  • No Need for Peptide Exchange Factors: Unlike other tetramer solutions, our Empty Loadable Tetramers don’t rely on peptide exchange factors, UV cleavage, or complex methods. They’re truly empty and ready to bind to your peptide of choice immediately.
  • Published in Science Immunology: Our cutting-edge technology was recently featured in Science Immunology, showcasing its breakthrough in MHC tetramer research published in Science Immunology.

 

Key Applications:

  • Traditional tetramer staining assays
  • T cell reactivity studies against neoantigens
  • Proprietary peptide research where confidentiality is key
  • Multi-color flow cytometry for detecting multiple T cell specificities

 

Key Benefits – Speed, Flexibility, and Affordability:

  • Instant Use: Add your peptide and stain T cells within minutes.
  • Global Shipping: Orders typically shipped within 24 hours.
  • Brighter Staining: Our proprietary stabilized MHC complex ensures superior brightness.
  • Freeze-Compatible Formulation: Allows you to aliquot and freeze for future use.
  • Multiple Colors: Available in a broad range of fluorochrome colors for flexible staining options.

 

 

Empty Loadable Tetramer
Empty Loadable MHC Tetramer – Just add peptide and stain

 

To order Empty Loadable Tetramers from Tetramer Store >> Press Here

 

Available ELT MHC Tetramers

Explore our high-quality, customizable MHC Tetramers. Each reagent is designed for flexibility, with empty loadable MHC molecules ready for your specific peptides.

 

ELT product List

Cat. No. MHC Type Peptide Sequence Antigen
MKb-016 H-2Kb Empty None
MKd-009 H-2Kd Empty None
HA02-070 HLA-A*02:01 Empty None
HB07-017 HLA-B*07:02 Empty None
HA11-006 HLA-A*11:01 Empty None
HA24-025 HLA-A*24:02 Empty None
HA03-001 HLA-A*03:01 Empty None

 

These reagents function like traditional MHC tetramers but give you the freedom to add your peptide antigen. The result is a highly flexible, customizable assay for detecting specific T cell responses, particularly useful for studying proprietary peptides or neoantigens.

 

Advantages of Empty Loadable Tetramers:

  • Improved Stability & Brightness: Our tetramers offer superior stability and brighter staining, giving you clearer results.
  • DIY Flexibility: Create custom tetramer specificities by adding your peptide of interest. This reduces costs and enhances experimental flexibility.
  • Ideal for Multi-Color Flow Cytometry: Perfect for combinatorial encoding and detecting multiple T cell specificities in a single sample.

 

Revolutionize Immunotherapy Development:

Our MHC Tetramers are crucial tools for epitope detection, immunotherapy, and vaccine development. Whether you’re monitoring disease progression, assessing immune responses, or isolating and expanding disease-specific T cells, our tetramers offer unmatched precision.

 

Why Choose Tetramer Assays?

  • Efficiency: Tetramer assays are quick and easy to perform.
  • Versatility: Suitable for both animal models and human studies.
  • Powerful Results: Allow for the physical isolation and study of antigen-specific T cells via flow cytometry and FACS sorting.

Take your research to the next level with our cost-effective, high-performance Empty Loadable MHC Tetramers.

 

Tetramer Specifications

Tetramer Store supply MHC Tetramers in various test sizes and the colors PE, BV421, BUV395, APC-Cy™7, APC, BV510, BV480, PE-Cy™5, PE-CF594, PE-Cy™7, PerCP-Cy™5.5, PerCP, FITC, BV605, BV650, BV786, APC-R700, BB515 and BUV737. For other colors, please enquire.