MHC Tetramer Technology

MHC Tetramer Technology: Convenient, Flexible, Specific, and Bright Detection of Antigen-Specific T Cells

At Tetramer Store, we offer a breakthrough in precision detection of CD8+ antigen-specific T cells, critical for advancing research in anti-viral and anti-cancer immunotherapies. Our innovative MHC Tetramers address the limitations of conventional tetramers—offering unmatched Convenience, Flexibility, Sensitivity, and Brightness.

Why Choose Our MHC Tetramers?

 

  • Extreme Stability and Bright Staining

Our proprietary stabilization technology ensures brighter, more specific staining of antigen-specific T cells, offering superior results compared to traditional tetramers. This enables more accurate and reliable monitoring of immune responses in your experiments.

 

  • Cost-Effective Solutions

We provide top-quality MHC Tetramers at an unbeatable value ensuring that you can perform more experiments without compromising on quality.

 

  • Broad Color Range for Flexible Research

Our MHC Tetramers are available in multiple colors, with custom color options to suit your specific research needs. This flexibility makes it easy to incorporate into multi-color flow cytometry, allowing for the simultaneous analysis of multiple T cell populations.

 

  • Rapid, Worldwide Delivery

Need reagents fast? We offer global shipping with off-the-shelf orders dispatched within 24 hours, ensuring that your research stays on schedule.

 

Revolutionary Empty Loadable MHC Tetramers

Our proprietary Empty Loadable MHC Tetramers offer unparalleled antigen flexibility, enabling on-demand customization for your assays. No UV cleavage, no exchange—just add your peptide of choice and stain your T cell samples instantly. This “DIY” solution simplifies workflows, especially for researchers working with multiple peptide antigens, neoantigens, or proprietary antigens.

Key Applications:

  • Conventional Tetramer Staining – compatible with all standard tetramer assay protocols
  • T Cell Reactivity – explore responses to neoantigens
  • Proprietary Peptide Antigens – ideal for researchers who need to keep peptides undisclosed
  • Combinatorial Multi-Color Flow Cytometry – analyze multiple T cell specificities in one experiment

Quality You Can Trust

All of our MHC Tetramers are produced to the highest standards, ensuring minimal lot-to-lot variation. Rigorous QC tests, including folding verification and virus peptide staining, guarantee performance and reliability before shipment. Our cutting-edge technology has been featured in Science Immunology, affirming our commitment to quality and innovation.

Transform your T cell research with Tetramer Store’s MHC Tetramers—fast, flexible, and reliable for all your immunotherapy and vaccine development needs.

 

We provide the broadest range of colors available including PE, BV421, BUV395, APC-Cy™7, APC, BV510, BV480, PE-Cy™5, PE-CF594, PE-Cy™7, PerCP-Cy™5.5, PerCP, FITC, BV605, BV650, BV786, APC-R700, BB515 and BUV737. For other colors, please enquire.