Publications using reagents supplied by Tetramer Store or Tetramer Shop, together with the foundational publication describing Empty Loadable MHC technology.
The list includes pMHC tetramers, Empty Loadable Tetramers, MHC monomers and a CD1d–lipid tetramer study. Catalogue numbers are historical identifiers reported in publications or retained from our reference list; they may differ from current ordering codes. A dash indicates that no catalogue number is listed here.
| Year | Publication | Product | Allele / peptide | Catalogue number |
|---|---|---|---|---|
| 2026 | Frei J et al. Chemically synthesized, non-capped and non-polyadenylated peptide-coding RNA efficiently induces antigen-specific CD8+ T cells. Nature Biomedical Engineering. doi:10.1038/s41551-026-01738-z | pMHC tetramer | H-2Kᵇ / SIINFEKL (PE) | — |
| 2026 | Fritz L et al. Differentiation-induced reduction in functional diversity restricts the ability of cytomegalovirus-specific CD8 T cells to eliminate virus-infected cells. eBioMedicine. doi:10.1016/j.ebiom.2025.106107 | Empty Loadable Tetramer | HLA-A*02:01; loaded with NLVPMVATV (CMV pp65; BV650) | HA02-070 |
| 2025 | Ebrahimi S et al. Targeting mutated KRAS by HLA-A*02:01 restricted anti-KRAS TCR-mimic CAR and bispecific T cell engager. Journal of Molecular Medicine. doi:10.1007/s00109-025-02585-2 | Peptide-loadable tetramer | HLA-A*02:01; KRAS peptide panel | — |
| 2025 | Kofoed SV et al. Preclinical evaluation of a CCL19 immune-potentiated DNA cancer vaccine. Cancer Immunology, Immunotherapy. doi:10.1007/s00262-025-04120-1 | pMHC tetramer | H-2Kᵈ / KFKASRASI (C1 neoantigen; PE) | — |
| 2025 | Sim HI et al. Modulating CD226 and PD-(L)1 pathways improves CMV-specific CD8+ T cell responses in the absence of IL-2. BMB Reports. doi:10.5483/BMBRep.2025-0041 | pMHC tetramer | HLA-A*02:01 / CMV pp65 (APC); Tetramer Store | — |
| 2025 | Nyesiga B et al. Antigenic peptide delivery to antigen-presenting cells using a CD40-coiled coil affinity-based platform. Drug Delivery. doi:10.1080/10717544.2025.2486340 | pMHC tetramer | H-2Kᵇ / SIINFEKL | MKb-001 |
| 2025 | Zhao P et al. Identification of shared neoantigens derived from frameshift mutations in the APC gene. Frontiers in Immunology. doi:10.3389/fimmu.2025.1574955 | pMHC tetramers | HLA-A*24:02; APC frameshift neoantigens | — |
| 2025 | Effenberger C et al. Bispecific antibody targeting shared indel-derived neoantigen of APC. Frontiers in Immunology. doi:10.3389/fimmu.2025.1574958 | Biotinylated MHC monomers | HLA-A*24:02; peptide-loaded and empty monomers. Tetramer Shop and MBL named as suppliers; empty monomer explicitly from Tetramer Shop. | — |
| 2025 | Lyu X et al. Direct delivery of immune modulators to tumour-infiltrating lymphocytes using engineered extracellular vesicles. Journal of Extracellular Vesicles. doi:10.1002/jev2.70035 | pMHC tetramer | H-2Kᵇ / OVA₂₅₇–₂₆₄ (SIINFEKL) | — |
| 2025 | Mauvais FX et al. Metallophilic marginal zone macrophages cross-prime CD8+ T cell-mediated protective immunity against blood-borne tumors. Immunity. doi:10.1016/j.immuni.2025.02.027 | pMHC tetramer | H-2Kᵇ / SIINFEKL | MKb-001 |
| 2025 | Velz J et al. Mapping naturally presented T cell antigens in medulloblastoma based on integrative multi-omics. Nature Communications. doi:10.1038/s41467-025-56268-0 | pMHC tetramers and MHC monomers | HLA-A*02:01; medulloblastoma-associated peptide panel | — |
| 2024 | Kortleve D et al. TCR-Engineered T Cells Directed against Ropporin-1 Constitute a Safe and Effective Treatment for Triple-Negative Breast Cancer. Cancer Discovery. doi:10.1158/2159-8290.CD-24-0168 | pMHC tetramers | HLA-A2; ROPN1 peptide panel | — |
| 2024 | Vietzen H et al. Torque teno viruses exhaust and imprint the human immune system via the HLA-E/NKG2A axis. Frontiers in Immunology. doi:10.3389/fimmu.2024.1447980 | Empty Loadable Tetramers | HLA-A*02:01; HLA-A*03:01; HLA-A*11:01; HLA-A*24:02 | HA02-070; HA03-001; HA11-006; HA24-025, respectively |
| 2024 | Wei P et al. An intranasal cationic liposomal polysaccharide vaccine elicits humoral immune responses against Streptococcus pneumoniae. Communications Biology. doi:10.1038/s42003-024-06806-1 | CD1d–lipid tetramer | Mouse CD1d / α-galactosylceramide (αGC) | MCD1d-001 |
| 2024 | Pavlidis MA et al. Refined analytical pipeline for the pharmacodynamic assessment of T-cell responses to vaccine antigens. Frontiers in Immunology. doi:10.3389/fimmu.2024.1404121 | Empty Loadable Tetramers | HLA-A*02:01; HLA-A*11:01 | HA02-070; HA11-006, respectively |
| 2024 | Stone ML et al. Hepatocytes coordinate immune evasion in cancer via release of serum amyloid A proteins. Nature Immunology. doi:10.1038/s41590-024-01820-1 | pMHC tetramer | H-2Kᵇ / SIINFEKL | MKb-001 |
| 2024 | Padoan B et al. NKp44/HLA-DP-dependent regulation of CD8 effector T cells by NK cells. Cell Reports. doi:10.1016/j.celrep.2024.114089 | pMHC tetramer | HLA-A*02:01 / CMV pp65 (APC) | HLA02-010 (as reported in the paper) |
| 2024 | Lazar K et al. Frequencies of activated T cell populations increase in breast milk of HCMV-seropositive mothers during local HCMV reactivation. Frontiers in Immunology. doi:10.3389/fimmu.2023.1258844 | pMHC tetramers | HLA-A*02:01 / NLVPMVATV (pp65); HLA-A*02:01 / VLEETSVML (IE1) | — |
| 2023 | Yarmarkovich M et al. Targeting of intracellular oncoproteins with peptide-centric CARs. Nature. doi:10.1038/s41586-023-06706-0 | Empty Loadable Tetramer | HLA-A*24:02 | HA24-025 |
| 2023 | Barrio-Calvo M et al. Targeting neoantigens to APC-surface molecules improves the immunogenicity and anti-tumor efficacy of a DNA cancer vaccine. Frontiers in Immunology. doi:10.3389/fimmu.2023.1234912 | pMHC tetramer | H-2Kᵈ / KFKASRASI | MKd-008 |
| 2023 | Kudling TV et al. Effective intravenous delivery of adenovirus armed with TNFα and IL-2 improves anti-PD-1 checkpoint blockade in non-small cell lung cancer. OncoImmunology. doi:10.1080/2162402X.2023.2241710 | pMHC tetramer | H-2Kᵇ / KMYQYARL | — |
| 2023 | Kamensek U et al. What We Learned about the Feasibility of Gene Electrotransfer for Vaccination on a Model of COVID-19 Vaccine. Pharmaceutics. doi:10.3390/pharmaceutics15071981 | pMHC tetramers | H-2Kᵇ / VNFNFNGL; H-2Kᵇ / LALLLLDRL; H-2Kᵇ / TSYKFESV | MKb-023; MKb-024; MKb-002, respectively |
| 2023 | Medici G et al. A T-cell antigen atlas for meningioma: novel options for immunotherapy. Acta Neuropathologica. doi:10.1007/s00401-023-02605-w | Empty Loadable Tetramer | HLA-A*02:01 | HA02-070 |
| 2023 | Viborg N et al. DNA based neoepitope vaccination induces tumor control in syngeneic mouse models. npj Vaccines. doi:10.1038/s41541-023-00671-5 | Empty Loadable Tetramers and custom pMHC multimers | H-2Kᵇ (loaded with SGFRYNVL or SIINFEKL); H-2Kᵈ and H-2Dᵈ custom neoepitope multimers | MKb-016 (H-2Kᵇ Empty Loadable) |
| 2023 | Kavazović I et al. Vaccination provides superior in vivo recall capacity of SARS-CoV-2-specific memory CD8 T cells. Cell Reports. doi:10.1016/j.celrep.2023.112395 | pMHC tetramers | HLA-A*02:01 / YLQPRTFLL; HLA-A*02:01 / GILGFVFTL | HA02-169; HA02-012, respectively |
| 2023 | Son ET et al. Screening self-peptides for recognition by mouse alloreactive CD8+ T cells using direct ex vivo multimer staining. STAR Protocols. doi:10.1016/j.xpro.2022.101943 | Empty Loadable Tetramer | H-2Kᵇ | MKb-016 |
| 2022 | Tian XM et al. BRAFV600E and BRAF-WT Specific Antitumor Immunity in Papillary Thyroid Cancer. Hormone and Metabolic Research. doi:10.1055/a-1971-7019 | pMHC tetramers | HLA-A*02:01 / GLATEKSRW, GLATEKSRWS, GLATVKSRW and GLATVKSRWS | HA02-164; HA02-165; HA02-166; HA02-167, respectively |
| 2022 | Jarzebska NT et al. RNA with chemotherapeutic base analogues as a dual-functional anti-cancer drug. OncoImmunology. doi:10.1080/2162402X.2022.2147665 | pMHC tetramer | H-2Kᵇ / SIINFEKL | MKb-001 |
| 2022 | Axelrod ML et al. T cells specific for α-myosin drive immunotherapy-related myocarditis. Nature. doi:10.1038/s41586-022-05432-3 | Empty Loadable Tetramer | H-2Kᵇ | MKb-016 |
| 2022 | Hägerbrand K et al. Bispecific antibodies targeting CD40 and tumor-associated antigens promote cross-priming of T cells resulting in an antitumor response superior to monospecific antibodies. Journal for ImmunoTherapy of Cancer. doi:10.1136/jitc-2022-005018 | pMHC tetramer | H-2Kᵇ / SIINFEKL | MKb-001 |
| 2022 | Chaisawangwong W et al. Cross-reactivity of SARS-CoV-2– and influenza A–specific T cells in individuals exposed to SARS-CoV-2. JCI Insight. doi:10.1172/jci.insight.158308 | pMHC tetramer | HLA-A*02:01 / SARS-CoV-2 epitope designated “LLY” | — |
| 2022 | Deak P et al. Robust tolerogenic dendritic cells via push/pull pairing of toll-like-receptor agonists and immunomodulators reduces EAE. Biomaterials. doi:10.1016/j.biomaterials.2022.121571 | pMHC tetramer | H-2Kᵇ / SIINFEKL | MKb-001 |
| 2022 | Carnaz Simões AM et al. Patients With Myeloproliferative Neoplasms Harbor High Frequencies of CD8 T Cell-Platelet Aggregates Associated With T Cell Suppression. Frontiers in Immunology. doi:10.3389/fimmu.2022.866610 | Empty Loadable Tetramer | HLA-A*02:01 | HA02-070 |
| 2022 | Fahad AS et al. Immortalization and functional screening of natively paired human T cell receptor repertoires. Protein Engineering, Design and Selection. doi:10.1093/protein/gzab034 | pMHC tetramers | Multiple specificities; supplier-specific allele allocation not established | — |
| 2022 | Bendtsen SK et al. Peptide vaccination activating Galectin-3-specific T cells offers a novel means to target Galectin-3-expressing cells in the tumor microenvironment. OncoImmunology. doi:10.1080/2162402X.2022.2026020 | Peptide-loaded HLA tetramers | Galectin-3 peptide assays; PE/APC tetramers from Tetramer Shop and in-house. Supplier-specific allele allocation not established. | — |
| 2021 | Bošnjak B et al. Intranasal Delivery of MVA Vector Vaccine Induces Effective Pulmonary Immunity Against SARS-CoV-2 in Rodents. Frontiers in Immunology. doi:10.3389/fimmu.2021.772240 | Empty Loadable Tetramer | H-2Kᵇ | MKb-016 |
| 2021 | Jarzebska NT et al. Lipofection with Synthetic mRNA as a Simple Method for T-Cell Activation/Assay. Viruses. doi:10.3390/v13071232 | Empty Loadable Tetramer | HLA-A*02:01 | HA02-070 |
| 2021 | Weiss AM et al. Site-specific antigen-adjuvant conjugation using cell-free protein synthesis enhances antigen presentation and CD8+ T-cell response. Scientific Reports. doi:10.1038/s41598-021-85709-1 | pMHC tetramer | H-2Kᵇ / SIINFEKL | MKb-001 |
| 2020 | Ferretti AP et al. Unbiased Screens Show CD8+ T Cells of COVID-19 Patients Recognize Shared Epitopes in SARS-CoV-2 that Largely Reside outside the Spike Protein. Immunity. doi:10.1016/j.immuni.2020.10.006 | Empty Loadable Tetramer | HLA-A*02:01 | HA02-070 |
| 2019 | Saini SK et al. Empty peptide-receptive MHC class I molecules for efficient detection of antigen-specific T cells. Science Immunology. doi:10.1126/sciimmunol.aau9039 | Foundational Empty Loadable MHC technology | HLA-A*02:01; HLA-A*24:02; H-2Kᵇ | HA02-070; HA24-025; MKb-016 (product mapping) |
Lazar et al. was published online on 3 January 2024 in the journal’s 2023 volume. Catalogue number HLA02-010 is reproduced as reported by Padoan et al. Supplier-specific reagent allocation is noted where publications combine purchased and in-house reagents.