Detect OVA/SIINFEKL-Specific T Cells with H-2Kb SIINFEKL Tetramers
Our H-2Kb SIINFEKL MHC tetramers are the ideal solution for detecting and tracking CD8+ T cells specific to the immunodominant SIINFEKL (OVA 257-264) peptide from ovalbumin (OVA). These tetramers are purpose-built for research involving OT-I cells in C57BL/6 mice or OT-I transgenic models.
Why Choose SIINFEKL?
Ovalbumin (OVA) is a widely used antigen for studying T cell-specific immune responses. During OVA processing, the SIINFEKL peptide is generated, which binds to H-2Kb MHC class I molecules, eliciting a potent CD8+ T cell response, particularly from OT-I cells. This makes SIINFEKL a gold standard for antigen-specific T cell research.
Key Features of H-2Kb/SIINFEKL MHC Tetramers
- Highly Specific Detection: Precisely identifies OT-I cells, enabling accurate tracking of antigen-specific immune responses.
- Reliable & Precise: Ensures consistent and sensitive detection of SIINFEKL-specific CD8+ T cells.
- Optimal for Research Models: Specifically designed for use with C57BL/6 mice and OT-I TCR transgenic models.
Applications
- T Cell Response Tracking: Detect and monitor T cell responses to OVA, ideal for immunotherapy, vaccine research, and immune response studies.
- Flow Cytometry & Immune Monitoring: Perfect for use in flow cytometry and other immune monitoring assays.
Order H-2Kb SIINFEKL MHC Tetramers for Your Research
Streamline your studies on antigen-specific T cell responses with our reliable H-2Kb SIINFEKL MHC tetramers.
| Cat. No. | MHC Type | Peptide Seq. | Antigen |
|---|---|---|---|
| MKb-001 | H-2Kb | SIINFEKL | Ovalbumin |
Take your research further—order today!
Specification of Tetramers
Tetramer Store supply MHC Tetramers in various test sizes and the colors PE, BV421, BUV395, APC, BV510, BV480, BV605, BV650, BV786, BB515 and BUV737. For other colors, please enquire.